|
Symbol Name ID |
Egln1
egl-9 family hypoxia-inducible factor 1 MGI:1932286 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased hematocrit |
Increased circulating hemoglobin concentration |
Increased red blood cell mass |
| Disease(s) Associated with EGLN1 | |||
| familial erythrocytosis 3 |
| Mouse Phenotypes | hematopoietic system phenotype |
enlarged spleen |
increased spleen weight |
abnormal definitive hematopoiesis |
extramedullary hematopoiesis |
increased erythroid progenitor cell number |
abnormal megakaryocyte progenitor cell morphology |
increased erythroblast number |
polycythemia |
increased hematocrit |
increased hemoglobin content |
abnormal nucleated erythrocyte cell number |
thrombocytopenia |
abnormal lymphocyte cell number |
increased leukocyte cell number |
abnormal spleen morphology |
abnormal splenic cell ratio |
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| Availability | Mouse Genotype | |||||||||||||||||
| Egln1Gt(RRG405)Byg/Egln1Gt(RRG405)Byg | * | |||||||||||||||||
| Egln1tm1.1Fsl/Egln1+ | ||||||||||||||||||
| Egln1tm2.2Fsl/Egln1+ | ||||||||||||||||||
| Egln1tm1.1Brei/Egln1tm1.1Brei Tg(CD68-icre)1Bwlx/0 (conditional) |
* | |||||||||||||||||
| Egln1tm1Kael/Egln1tm1Kael Tg(CAG-cre/Esr1*)5Amc/0 (conditional) |
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| Egln1tm2.1Fsl/Egln1tm2.1Fsl Pax3tm1(cre)Joe/Pax3+ (conditional) |
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| Egln1tm2.1Fsl/Egln1tm2.1Fsl Commd10Tg(Vav1-icre)A2Kio/Commd10+ (conditional) |
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| Egln1tm2.1Fsl/Egln1tm2.1Fsl Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+ (conditional) |
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| Egln1tm2Fong/Egln1tm2Fong Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+ (conditional) |
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| Egln1tm2.1Fsl/Egln1+ Pax3tm1(cre)Joe/Pax3+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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